Agitated Vessels for Fermentation
Agitated vessels for fermentation are specialized bioreactors designed to support microbial growth and product formation through controlled agitation, aeration, and environmental conditions. These vessels provide gentle yet effective mixing to maintain cell viability, enhance oxygen transfer, and ensure uniform nutrient distribution.
Why are Agitated Vessels Needed for Fermentation?
Fermentation requires agitated vessels that balance mixing effectiveness with cell protection. Agitation maintains cells in suspension, enhances oxygen transfer for aerobic processes, distributes nutrients uniformly, and provides temperature control. Proper vessel design is critical for cell viability and process productivity.
Industries Using Agitated Vessels for Fermentation
Common industries include:
- Biotechnology
- Pharmaceutical
- Food and Beverage
- Biofuels
- Industrial Enzymes
- Brewing
Specifications and Characteristics
At Roben, Mfg, Inc., we offer comprehensive options including:
- Low-shear impeller options
- Integrated aeration systems
- Sterile design with CIP/SIP
- DO and pH control capability
- Scalable designs from pilot to production
Certifications and Standards
Our agitated vessels are designed and manufactured in accordance with stringent industry standards:
- ASME Boiler and Pressure Vessel Code: Pressure vessel design and fabrication
- FDA cGMP Guidelines: Pharmaceutical manufacturing compliance
- 3-A Sanitary Standards: Food and dairy equipment
- ISO 9001: Quality management system certification
- CE Marking: European compliance certification
- ATEX Directive: Explosive atmosphere certification where applicable
Agitated Vessels for Fermentation FAQs
How do you balance oxygen transfer and shear damage?
Oxygen transfer and shear are balanced through impeller selection (low-shear dispersers), optimized tip speed, proper power input, and staged impeller systems. Rushton turbines provide oxygen transfer; upper hydrofoils provide circulation with minimal shear. CFD identifies high-shear zones for elimination.
What scale-up considerations apply to fermenters?
Fermenter scale-up maintains critical parameters including oxygen transfer (kLa), mixing time, power per volume, and tip speed. Geometric similarity may not provide identical performance at different scales. We design fermenters with validated scale-up methodology for predictable production performance.
Contact Roben, Mfg, Inc.
For more information about our agitated vessel solutions or to request a quote, please contact Roben, Mfg, Inc. today. Our experienced engineering team utilizes advanced CFD software to optimize agitator designs for your specific mixing requirements.
Phone: (732) 364-6000 | Email: sales@robenmfg.com
760 Vassar Ave, Lakewood, NJ 08701
