Agitated Vessels for Biotechnology
Agitated vessels for biotechnology are specialized bioreactors and fermenters designed to support cell culture and fermentation processes through controlled, gentle agitation. These vessels provide mixing that maintains cell viability, enhances oxygen transfer, and ensures uniform conditions for optimal biological production.
Why are Agitated Vessels Needed for Biotechnology?
Biotechnology processes require agitated vessels that balance mixing effectiveness with cell protection. Agitation must maintain cells in suspension, provide adequate oxygen transfer, and ensure uniform nutrient distribution while minimizing shear damage to sensitive cultures. Proper vessel design is critical for process success.
Agitated Vessel Types for Biotechnology
Roben, Mfg, Inc. manufactures various agitated vessel types for biotechnology:
- Fermenters
- Bioreactors
- Cell Culture Vessels
- Mixing Tanks
- Buffer Preparation Vessels
- Harvest Tanks
Biotechnology Applications
Common applications include:
- Microbial fermentation
- Cell culture
- Enzyme production
- Vaccine manufacturing
- Monoclonal antibody production
- Gene therapy vectors
Certifications and Standards
Our agitated vessels are designed and manufactured in accordance with stringent industry standards:
- ASME Boiler and Pressure Vessel Code: Pressure vessel design and fabrication
- FDA cGMP Guidelines: Pharmaceutical manufacturing compliance
- 3-A Sanitary Standards: Food and dairy equipment
- ISO 9001: Quality management system certification
- CE Marking: European compliance certification
- ATEX Directive: Explosive atmosphere certification where applicable
Agitated Vessels for Biotechnology FAQs
How do you protect shear-sensitive cells?
Cell protection uses low-shear impeller designs, optimized tip speeds, appropriate power input, and CFD analysis to minimize high-shear zones. For extremely sensitive cultures, alternatives like air-lift or wave bioreactor technologies eliminate impeller shear entirely. We design systems matched to your culture sensitivity.
What containment options are available?
Containment options include single-use systems, hard-piped contained vessels, sterile barriers on all penetrations, contained sampling systems, and HEPA-filtered venting. Design supports biosafety requirements from BSL-1 through BSL-3. We provide complete containment solutions for your organism classification.
Contact Roben, Mfg, Inc.
For more information about our agitated vessel solutions or to request a quote, please contact Roben, Mfg, Inc. today. Our experienced engineering team utilizes advanced CFD software to optimize agitator designs for your specific mixing requirements.
Phone: (732) 364-6000 | Email: sales@robenmfg.com
760 Vassar Ave, Lakewood, NJ 08701
